what is the main idea of the passage about sickle cell anemia
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HESI A2

Reading Comprehension Practice Test HESI A2

1. What is the main idea of the passage about Sickle-Cell Anemia?

Correct answer: D

Rationale: The correct answer is D. The passage focuses on describing sickle-cell anemia as a painful and inherited disease. It details how the abnormal sickle-shaped cells cause symptoms like bone pain, fever, and fatigue. While bone pain is mentioned as a symptom, it is not the main idea of the passage. Choice A is incorrect. Choice B, which mentions oxygen transport, is not the main idea but a general concept. Choice C, stating genetically inherited diseases affect thousands, is too broad and does not focus on the specifics of sickle-cell anemia. Therefore, D is the most precise choice.

2. What is the major difference between matter at the nanoscale and matter at larger scales such as millimeters or inches?

Correct answer: B

Rationale: The correct answer is B. Matter at the nanoscale exhibits unique and special characteristics that distinguish it from matter at larger scales. This can include properties like increased surface area, different melting points, altered conductivity, and enhanced reactivity. Choice A is incorrect as metals at the nanoscale can be more rigid compared to their larger scale counterparts. Choice C is incorrect because matter at the nanoscale has properties that are distinct from both atomic and larger scales. Choice D is incorrect as there are significant differences in how matter behaves and interacts at the nanoscale compared to larger scales.

3. What is implied by the author's mention of the Kayapo people in the passage on the Amazon Rainforest?

Correct answer: B

Rationale: The mention of the Kayapo people in the passage highlights how they farm in an environmentally friendly manner. Instead of using chemicals, they enrich the soil by burning wood and plant banana trees, attracting wasps that feed on harmful insects. This sustainable farming practice showcases their efforts to coexist with the rainforest ecosystem without causing harm. The other choices are incorrect: A is refuted by the passage as the Kayapo people are described as farming in an environmentally friendly way, C is incorrect as the passage does not mention the Kayapo people contributing to deforestation, and D is not supported by the text as there is no mention of the Kayapo people hunting animals for survival.

4. What is the writer’s primary purpose in writing this essay?

Correct answer: C

Rationale: The primary purpose of the essay is to inform the reader about how the cardiovascular system regulates blood pressure. The essay provides detailed explanations about the components of the cardiovascular system that regulate blood pressure, such as baroreceptors, chemoreceptors, and the kidneys. Choices A and B are incorrect because the essay does not focus on discussing the dangers of high blood pressure or its correlation with a higher risk of heart attack. Choice D is incorrect as the essay does not aim to persuade the reader to control their blood pressure but rather to educate them on the regulatory mechanisms of the cardiovascular system.

5. Which might be a good title for this passage?

Correct answer: D

Rationale: The title "The Debate over Barefoot Running" encapsulates the central theme of the passage, which explores both the advantages and disadvantages of barefoot running. It effectively summarizes the discussions around differing opinions and the lack of consensus on this topic. Other titles do not accurately reflect the primary focus of the essay, making D the most suitable choice.

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