what is the main idea of the passage about sickle cell anemia
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Nursing Elites

HESI A2

Reading Comprehension Practice Test HESI A2

1. What is the main idea of the passage about Sickle-Cell Anemia?

Correct answer: D

Rationale: The correct answer is D. The passage focuses on describing sickle-cell anemia as a painful and inherited disease. It details how the abnormal sickle-shaped cells cause symptoms like bone pain, fever, and fatigue. While bone pain is mentioned as a symptom, it is not the main idea of the passage. Choice A is incorrect. Choice B, which mentions oxygen transport, is not the main idea but a general concept. Choice C, stating genetically inherited diseases affect thousands, is too broad and does not focus on the specifics of sickle-cell anemia. Therefore, D is the most precise choice.

2. What is the meaning of the word overturn in the last paragraph of the passage?

Correct answer: B

Rationale: The word "overturn" means to invalidate or negate existing guidelines. In this context, the passage questions whether the findings of the study are substantial enough to change established medical recommendations regarding caffeine intake during pregnancy, making option B the appropriate choice.

3. What conclusion can the reader draw after reading the passage about The Sleep Workout?

Correct answer: B

Rationale: The correct answer is B because the passage highlights that insufficient sleep could lead to an increased risk of obesity. The passage emphasizes the importance of uninterrupted sleep in muscle development and mentions that inadequate sleep is linked to lowered levels of leptin, a hormone that controls appetite. This imbalance in leptin due to lack of sleep can lead to increased cravings for carbohydrates, contributing to obesity. Choice A is incorrect as the passage stresses the significance of both uninterrupted sleep and getting enough sleep for muscle growth. Choice C is incorrect because the passage clearly states that human growth hormone (HGH) is essential for muscle development. Choice D is incorrect as leptin is not essential for building muscle but is mentioned in the passage as a hormone related to controlling appetite and its link to inadequate sleep and obesity.

4. Which might be a good title for this passage?

Correct answer: D

Rationale: The title "The Debate over Barefoot Running" encapsulates the central theme of the passage, which explores both the advantages and disadvantages of barefoot running. It effectively summarizes the discussions around differing opinions and the lack of consensus on this topic. Other titles do not accurately reflect the primary focus of the essay, making D the most suitable choice.

5. Which statement could be inferred from the passage?

Correct answer: A

Rationale: The correct answer is A. The passage mentions a previous study by the same team on the connection between exercise and energy, indicating that the lab had conducted such research before. Choice B is incorrect because the passage actually states that low-impact exercise can help reduce fatigue in patients with serious health conditions. Choice C is incorrect as the passage indicates that an increase in energy levels does correspond to a reduction in fatigue. Choice D is incorrect as the passage does not provide information on the exact number of participants in each group.

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