what is the main idea of the passage about sickle cell anemia
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HESI A2

Reading Comprehension Practice Test HESI A2

1. What is the main idea of the passage about Sickle-Cell Anemia?

Correct answer: D

Rationale: The correct answer is D. The passage focuses on describing sickle-cell anemia as a painful and inherited disease. It details how the abnormal sickle-shaped cells cause symptoms like bone pain, fever, and fatigue. While bone pain is mentioned as a symptom, it is not the main idea of the passage. Choice A is incorrect. Choice B, which mentions oxygen transport, is not the main idea but a general concept. Choice C, stating genetically inherited diseases affect thousands, is too broad and does not focus on the specifics of sickle-cell anemia. Therefore, D is the most precise choice.

2. What is the author’s attitude toward the use of cosmetics?

Correct answer: D

Rationale: The author’s tone is disapproving, as evidenced by the focus on the negative consequences of using cosmetics with harmful ingredients. The passage discusses historical and contemporary health issues related to beauty practices, indicating a critical stance on the use of cosmetics that compromise health, which supports option D.

3. What conclusion can the reader draw after reading the passage about The Sleep Workout?

Correct answer: B

Rationale: The correct answer is B because the passage highlights that insufficient sleep could lead to an increased risk of obesity. The passage emphasizes the importance of uninterrupted sleep in muscle development and mentions that inadequate sleep is linked to lowered levels of leptin, a hormone that controls appetite. This imbalance in leptin due to lack of sleep can lead to increased cravings for carbohydrates, contributing to obesity. Choice A is incorrect as the passage stresses the significance of both uninterrupted sleep and getting enough sleep for muscle growth. Choice C is incorrect because the passage clearly states that human growth hormone (HGH) is essential for muscle development. Choice D is incorrect as leptin is not essential for building muscle but is mentioned in the passage as a hormone related to controlling appetite and its link to inadequate sleep and obesity.

4. What is the meaning of the word innocuous as used in the first paragraph?

Correct answer: B

Rationale: The word "innocuous" in this context means harmless, indicating that most nail abnormalities are not dangerous.

5. Which might be a good title for this passage?

Correct answer: D

Rationale: The title "The Debate over Barefoot Running" encapsulates the central theme of the passage, which explores both the advantages and disadvantages of barefoot running. It effectively summarizes the discussions around differing opinions and the lack of consensus on this topic. Other titles do not accurately reflect the primary focus of the essay, making D the most suitable choice.

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