what is the main idea of the passage about sickle cell anemia

HESI A2

Reading Comprehension Practice Test HESI A2

1. What is the main idea of the passage about Sickle-Cell Anemia?

A. Bone pain is a symptom of sickle-cell anemia.
B. Sickle-cell anemia affects oxygen transport in the body.
C. Sickle-cell anemia is a genetically inherited disease.
D. Sickle-cell anemia is a painful, inherited disease.

Correct answer: D

Rationale: The correct answer is D. The passage focuses on describing sickle-cell anemia as a painful and inherited disease. It details how the abnormal sickle-shaped cells cause symptoms like bone pain, fever, and fatigue. While bone pain is mentioned as a symptom, it is not the main idea of the passage. Choice A is incorrect. Choice B, which mentions oxygen transport, is not the main idea but a general concept. Choice C, stating genetically inherited diseases affect thousands, is too broad and does not focus on the specifics of sickle-cell anemia. Therefore, D is the most precise choice.

2. Which of the following statements is an opinion related to MRSA?

A. Hand-washing stations are one means of combating MRSA infection.
B. Not all Staphylococcus bacteria are resistant to antibiotics.
C. Hospitals in the United States should quickly adopt the use of new germ-fighting textiles.
D. MRSA infection kills more people in the United States than does HIV/AIDS.

Correct answer: C

Rationale: The correct answer is C because it is an opinion rather than a verifiable fact. The statement suggests a recommendation for hospitals to adopt new germ-fighting textiles swiftly, which is a subjective viewpoint and not objectively measurable. Choices A and B are factual statements regarding combating MRSA infection and antibiotic resistance, respectively. Choice D provides a comparison of MRSA infection with HIV/AIDS, which is a factual statement based on statistical data. Therefore, C is the only choice that presents an opinion rather than a fact.

3. Which of the following is not listed as a detail in the passage about microbes?

A. Babies are born coated with germs from the birth canal.
B. Mice and humans respond to microbes differently.
C. Few people share the same microbes in the same quantities.
D. Human bodies contain far more microbes than they do cells.

Correct answer: B

Rationale: The correct answer is B because the passage does not detail that mice and humans respond to microbes differently. The passage discusses how laboratory mice required a particular strain of bacteria to help their immune systems function correctly, indicating a difference in how mice and humans respond to microbes. Choices A, C, and D are all details mentioned in the passage: A discusses babies being coated with germs from the birth canal, C talks about the variation in microbes among individuals, and D states that human bodies contain more microbes than cells.

4. In this passage, which of the following is not mentioned as a role of HGH in the human body?

A. Regulating the metabolism.
B. Stimulating the immune system.
C. Regulating leptin, an appetite-controlling hormone.
D. Facilitating calcium retention.

Correct answer: C

Rationale: The correct answer is C: Regulating leptin, an appetite-controlling hormone. In the provided passage, it is stated that human growth hormone (HGH) is essential for regulating metabolism, building muscle, facilitating calcium retention, and stimulating the immune system. However, leptin is not mentioned as directly regulated by HGH. Instead, the passage discusses how inadequate sleep can lead to lowered levels of leptin, affecting appetite control. Choices A, B, and D are all roles of HGH explicitly mentioned in the passage, making them incorrect answers. Therefore, C is the correct choice as it was not directly linked to HGH in the passage.

5. What is the author’s primary purpose in writing the essay?

A. To persuade the reader to have an ECG
B. To entertain the reader with a heartwarming story
C. To inform the reader how an electrocardiograph reads the electric currents emitted by the heart
D. To analyze the difference between the SA node and the AV node

Correct answer: C

Rationale: The author's primary purpose in writing the essay is to inform the reader about how an electrocardiograph reads the electric currents emitted by the heart. Choice A is incorrect because there is no attempt to persuade the reader to have an ECG. Choice B is incorrect because the essay is focused on providing information rather than entertaining with a heartwarming story. Choice D is incorrect as the essay does not primarily analyze the difference between the SA node and the AV node; instead, it focuses on explaining how an electrocardiograph reads electric currents from the heart.