what is the main idea of the passage about sickle cell anemia
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HESI A2

Reading Comprehension Practice Test HESI A2

1. What is the main idea of the passage about Sickle-Cell Anemia?

Correct answer: D

Rationale: The correct answer is D. The passage focuses on describing sickle-cell anemia as a painful and inherited disease. It details how the abnormal sickle-shaped cells cause symptoms like bone pain, fever, and fatigue. While bone pain is mentioned as a symptom, it is not the main idea of the passage. Choice A is incorrect. Choice B, which mentions oxygen transport, is not the main idea but a general concept. Choice C, stating genetically inherited diseases affect thousands, is too broad and does not focus on the specifics of sickle-cell anemia. Therefore, D is the most precise choice.

2. Which statement could be inferred from the passage?

Correct answer: A

Rationale: The correct answer is A. The passage mentions a previous study by the same team on the connection between exercise and energy, indicating that the lab had conducted such research before. Choice B is incorrect because the passage actually states that low-impact exercise can help reduce fatigue in patients with serious health conditions. Choice C is incorrect as the passage indicates that an increase in energy levels does correspond to a reduction in fatigue. Choice D is incorrect as the passage does not provide information on the exact number of participants in each group.

3. The author describes cosmetics in each of the following cultures EXCEPT ___________.

Correct answer: D

Rationale: The author provides descriptions of cosmetic practices in Greek, Egyptian, and Roman cultures but does not mention Native American practices regarding cosmetics. This absence of information about Native American culture leads to the conclusion that option D is correct since it reflects a lack of discussion on that specific culture.

4. A reader might infer from this passage that the organization ___________.

Correct answer: D

Rationale: The passage never says whether or not the CDC succeeded in its original mission (choice A) or whether it continued to be led by doctors (choice B). Inferring either of those things would be a leap unsupported by the text. Choice C is countered by information in the final

5. Choose the best summary of the passage about microbes.

Correct answer: C

Rationale: The correct answer is C. The passage emphasizes the importance of certain bacteria for a properly functioning immune system. It discusses how harmless bacteria play a crucial role in defending the body against pathogens. Choice A is incorrect as it focuses on the immune system's response to certain types of bacteria in lower organisms, not the overall importance of bacteria for immunity. Choice B is incorrect as it mainly discusses bacteriotherapy in relation to the reconstruction of a damaged colon, rather than the broader role of bacteria in immune system health. Choice D is incorrect as it only talks about the process of replacing harmful bacteria with harmless ones, missing the key point about the necessity of certain bacteria for immune system function.

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