Nursing Elites

1. How does the structure of centromeres contribute to chromosome movement during mitosis?

• A. The centromere provides a binding site for spindle fibers, allowing chromosomes to be attached and manipulated.
• B. The centromere serves as a dividing point between sister chromatids, ensuring their separation during anaphase.
• C. The centromere maintains chromosome stability by preventing chromosomal breaks and rearrangements.
• D. The centromere plays a role in DNA replication, ensuring accurate copying of the genetic material.

Correct answer: A

Rationale: A) The centromere provides a binding site for spindle fibers, which are microtubules that help move chromosomes during cell division. This attachment allows the chromosomes to be pulled towards opposite poles of the cell during mitosis. Therefore, the structure of centromeres directly contributes to chromosome movement during mitosis by facilitating the attachment and manipulation of chromosomes by the spindle fibers. B) While the centromere does serve as a dividing point between sister chromatids, ensuring their separation during anaphase, this function is more related to the segregation of chromosomes rather than their movement. C) The centromere does play a role in maintaining chromosome stability by ensuring proper chromosome segregation, but it is not primarily responsible for preventing chromosomal breaks and rearrangements. D) The centromere is not directly involved in DNA replication. Its main function is

2. Which of the following functions would be most affected by laryngeal damage?

• A. Blinking
• B. Walking
• C. Singing
• D. Hearing

Correct answer: C

Rationale: Laryngeal damage would most affect the function of singing. The larynx, or voice box, houses the vocal cords responsible for producing sound during singing. Damage to the larynx can impair the ability to phonate and control pitch, tone, and quality of the voice, which are crucial for singing. Choices A, B, and D are unrelated to the larynx. Blinking is controlled by the facial nerve, walking involves motor functions and coordination, and hearing is related to the ear structures and auditory nerves.

3. Which hormone, produced by the pancreas, acts in opposition to insulin by increasing blood sugar levels?

• A. Insulin
• B. Glucagon
• C. Cortisol
• D. Thyroxine

Correct answer: B

Rationale: Glucagon is the correct answer. Produced by the pancreas, glucagon acts in opposition to insulin by increasing blood sugar levels. Glucagon promotes the breakdown of glycogen into glucose in the liver, leading to the release of glucose into the bloodstream. Insulin, on the other hand, lowers blood sugar levels by facilitating the uptake of glucose into cells. Cortisol is a hormone produced by the adrenal glands, not the pancreas, and is involved in stress response and metabolism. Thyroxine is a hormone produced by the thyroid gland and is primarily responsible for regulating metabolism.

4. Which structure in the lungs is the site of gas exchange?

• A. Trachea
• B. Alveoli
• C. Bronchioles
• D. Diaphragm

Correct answer: B

Rationale: The correct answer is B: Alveoli. Alveoli are tiny air sacs in the lungs where gas exchange occurs. Oxygen from inhaled air diffuses into the bloodstream, while carbon dioxide from the blood is released into the alveoli to be exhaled. The trachea (Choice A) is the windpipe that carries air to and from the lungs, but it is not involved in gas exchange. Bronchioles (Choice C) are small air passages within the lungs that branch off from the bronchi, leading air to the alveoli but not directly involved in gas exchange. The diaphragm (Choice D) is a muscle below the lungs that helps in breathing by expanding and contracting the chest cavity, but it is not the site of gas exchange.

5. How can a single gene mutation lead to multiple phenotypes depending on the organism?

• A. Pleiotropy describes the effect of one gene influencing multiple seemingly unrelated traits.
• B. Epigenetics involves environmental factors modifying gene expression without altering the DNA sequence.
• C. Genetic drift refers to random changes in allele frequencies within a population.
• D. Gene regulation controls the timing and level of gene expression within an organism.

Correct answer: A

Rationale: A single gene mutation can lead to multiple phenotypes through pleiotropy, where one gene influences diverse traits or functions in an organism. This phenomenon occurs when the mutated gene affects different biochemical pathways, developmental processes, or cellular functions, resulting in a cascade of downstream effects that manifest as a variety of phenotypic outcomes. Choice B, epigenetics, involves modifications in gene expression influenced by environmental factors without altering the DNA sequence, which is not directly related to the question about single gene mutations causing multiple phenotypes. Choice C, genetic drift, refers to random changes in allele frequencies within a population, which is unrelated to the impact of a single gene mutation on multiple phenotypes. Choice D, gene regulation, focuses on controlling the timing and level of gene expression within an organism, which is not directly addressing how a single gene mutation can lead to diverse phenotypes.

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