Nursing Elites

1. How does the structure of centromeres contribute to chromosome movement during mitosis?

• A. The centromere provides a binding site for spindle fibers, allowing chromosomes to be attached and manipulated.
• B. The centromere serves as a dividing point between sister chromatids, ensuring their separation during anaphase.
• C. The centromere maintains chromosome stability by preventing chromosomal breaks and rearrangements.
• D. The centromere plays a role in DNA replication, ensuring accurate copying of the genetic material.

Correct answer: A

Rationale: A) The centromere provides a binding site for spindle fibers, which are microtubules that help move chromosomes during cell division. This attachment allows the chromosomes to be pulled towards opposite poles of the cell during mitosis. Therefore, the structure of centromeres directly contributes to chromosome movement during mitosis by facilitating the attachment and manipulation of chromosomes by the spindle fibers. B) While the centromere does serve as a dividing point between sister chromatids, ensuring their separation during anaphase, this function is more related to the segregation of chromosomes rather than their movement. C) The centromere does play a role in maintaining chromosome stability by ensuring proper chromosome segregation, but it is not primarily responsible for preventing chromosomal breaks and rearrangements. D) The centromere is not directly involved in DNA replication. Its main function is

2. Diabetes mellitus is a chronic condition affecting blood sugar control. What is the main type of hormone deficiency associated with type 1 diabetes?

• A. Insulin
• B. Glucagon
• C. Estrogen
• D. Testosterone

Correct answer: A

Rationale: The correct answer is A: Insulin. Type 1 diabetes is characterized by the body's inability to produce insulin, the hormone responsible for regulating blood sugar levels. Insulin deficiency in type 1 diabetes leads to high blood sugar levels as the body cannot effectively utilize glucose for energy. Glucagon (Choice B) is a hormone that works opposite to insulin, raising blood sugar levels. Estrogen (Choice C) and testosterone (Choice D) are not directly involved in blood sugar control or the pathophysiology of type 1 diabetes.

3. Which of the following situations represents work being done on an object?

• A. Pushing against a wall without moving it
• B. Carrying a heavy object without lifting it
• C. Lifting a box to place it on a shelf
• D. Holding a book stationary in your hand

Correct answer: C

Rationale: Work is defined as the product of the force applied to an object and the distance over which the force is applied. In the situation of lifting a box to place it on a shelf, work is being done on the object. This is because lifting the box involves applying a force over a distance (the height of the shelf). The force applied to lift the box results in work being done on the object by raising it against the force of gravity. Choices A, B, and D do not involve work being done on the object as they either do not involve movement against a force (A, D) or do not cover distance against a force (B).

4. Which level of protein structure is defined by the folds and coils of the protein's polypeptide backbone?

• A. Primary
• B. Secondary
• C. Tertiary
• D. Quaternary

Correct answer: B

Rationale: The correct answer is B: Secondary. The secondary structure of a protein is defined by the folding and coiling of the polypeptide backbone into structures like alpha helices and beta sheets. Secondary structure primarily involves interactions such as hydrogen bonding within the backbone. This level of protein structure is distinct from primary structure (A) which refers to the linear sequence of amino acids, tertiary structure (C) which involves the overall 3D arrangement of a single polypeptide chain, and quaternary structure (D) which pertains to the interaction between multiple polypeptide chains in a protein complex.

5. A collection of organs working together to perform a specific physiological function is known as a(n):

• A. Tissue
• B. Organ system
• C. Organelle
• D. Organ

Correct answer: B

Rationale: An organ system is a group of organs that work together to perform specific functions in the body. Each organ within the system has a unique role, but they collaborate to achieve a common physiological function. This collaboration allows the body to carry out complex processes efficiently, demonstrating the interconnectedness and interdependence of different organs within the system. Choice A, 'Tissue,' refers to a group of cells that work together to perform a specific function, not a collection of organs. Choice C, 'Organelle,' is a subunit within a cell that has a specific function and is not a collection of organs. Choice D, 'Organ,' is a single structure composed of different tissues that performs a specific function, not a collection of organs working together.

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