one drug can alter the absorption of another drug one drug increases intestinal motility which effect does this have on the second drug
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Nursing Elites

NCLEX-PN

NCLEX-PN Quizlet 2023

1. One drug can alter the absorption of another drug. One drug increases intestinal motility. Which effect does this have on the second drug?

Correct answer: D

Rationale: When one drug increases intestinal motility, it accelerates the movement of the second drug through the system. Since most oral medications are absorbed in the intestine, the faster transit time decreases the absorption of the second drug. Therefore, less of the second drug is absorbed. Choice A is incorrect because the increased gut motility does affect the absorption of the second drug. Choice C is incorrect as the effect of increased intestinal motility on drug absorption can be predicted based on pharmacokinetic principles. Choice B is incorrect as increased gut motility would not increase but decrease the absorption of the second drug.

2. A nurse is caring for a client with an elevated cortisol level. The nurse can expect the client to exhibit symptoms of:

Correct answer: C

Rationale: Elevated cortisol levels can lead to sodium and fluid retention and potassium deficit, resulting in urinary deficit. This imbalance in electrolytes and fluid can cause a decrease in urinary output. Choices B, hyperpituitarism, and D, hyperthyroidism, are incorrect as they do not directly relate to the symptoms expected with elevated cortisol levels. Option A, urinary excess, is also incorrect as high cortisol levels typically lead to fluid retention and urinary deficit, not excess.

3. Which sexually transmitted disease, sometimes referred to as the silent STD, is more common than gonorrhea and a leading cause of PID?

Correct answer: D

Rationale: The correct answer is Chlamydia. Chlamydia is a common sexually transmitted infection that can often be asymptomatic, earning it the nickname 'silent STD.' It is more common than gonorrhea and is a leading cause of Pelvic Inflammatory Disease (PID). Genital herpes (Choice A) is a viral infection, not a bacterial STD like chlamydia. Trichomoniasis (Choice B) is a parasitic infection and not commonly associated with causing PID. Syphilis (Choice C) is a bacterial infection but is not as common as chlamydia and is not a leading cause of PID.

4. During a screening on a patient with a recent cast on the left lower extremity, which of the following statements should the nurse be most concerned about?

Correct answer: B

Rationale: The correct answer is B because pain in the left calf could indicate a potential neurovascular complication related to the casted extremity. It could suggest issues such as compartment syndrome or impaired circulation. Option A is not as concerning since not elevating the extremity may lead to swelling but is not an immediate concern. Option C indicates itching, which is common with casts and not as concerning as potential neurovascular issues. Option D, regarding arthritis in the wrists, is unrelated to the lower extremity issue being screened for.

5. Which statement best describes electrolytes in intracellular and extracellular fluid?

Correct answer: A

Rationale: Electrolytes are distributed unequally between intracellular and extracellular fluids. Sodium concentration is higher in extracellular fluid, while potassium concentration is higher in intracellular fluid. Therefore, the correct answer is 'There is a greater concentration of sodium in extracellular fluid and potassium in intracellular fluid.' Choices B, C, and D are incorrect because they do not accurately describe the typical distribution of sodium and potassium between intracellular and extracellular fluid.

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