NCLEX-PN
NCLEX-PN Quizlet 2023
1. A client needs to rapidly achieve a therapeutic plasma drug concentration of a medication. Rather than wait for steady state to be achieved, the physician might order:
- A. a maintenance dose.
- B. a loading dose.
- C. a medication with no first-pass effect.
- D. the medication to be given intravenously.
Correct answer: B
Rationale: To rapidly achieve a therapeutic plasma drug concentration, a loading or priming dose is ordered. This dose quickly establishes the desired drug level. It is calculated by multiplying the volume of distribution by the desired plasma drug concentration. A maintenance dose, like choice A, is used to maintain the therapeutic level after the loading dose. Waiting for steady state without a loading dose would take five drug half-lives. Choice C, a medication with no first-pass effect, does not directly address the need for rapid attainment of therapeutic levels. While intravenous administration (choice D) offers excellent bioavailability, a single dose by this route may not achieve the desired therapeutic plasma concentration as rapidly as a loading dose.
2. The drug of choice to decrease uric acid levels is:
- A. prednisone (Colisone)
- B. allopurinol (Zyloprim)
- C. indomethacin (Indocin)
- D. hydrochlorothiazide (HydroDiuril)
Correct answer: B
Rationale: The correct answer is allopurinol (Zyloprim) as it is a xanthine oxidase inhibitor that decreases uric acid formation. Allopurinol is commonly used to manage gout by lowering uric acid levels. Prednisone is a corticosteroid used to decrease inflammation, not to lower uric acid levels. Indomethacin is an analgesic, anti-inflammatory, and antipyretic agent, but it is not the drug of choice for lowering uric acid levels. Hydrochlorothiazide is a thiazide diuretic used to treat hypertension and edema, not to decrease uric acid levels.
3. A nurse suspects a patient is developing Bell's Palsy. The nurse wants to test the function of cranial nerve VII. Which of the following would be the most appropriate testing procedures?
- A. Test the taste sensation over the back of the tongue and activation of the facial muscles.
- B. Test the taste sensation over the front of the tongue and activation of the facial muscles.
- C. Test the sensation of the facial muscles and sensation of the back of the tongue.
- D. Test the sensation of the facial muscles and sensation of the front of the tongue.
Correct answer: B
Rationale: The facial nerve (VII) is responsible for motor function to the face and sensory function to the anterior two-thirds of the tongue. Therefore, to appropriately test the function of cranial nerve VII, the most appropriate testing procedures involve assessing the taste sensation over the front of the tongue (sensory) and activation of the facial muscles (motor). Option B, 'Test the taste sensation over the front of the tongue and activation of the facial muscles,' is the correct answer. Choices A, C, and D are incorrect because they do not involve the correct combination of sensory testing over the front of the tongue and motor activation of the facial muscles, which are key functions associated with cranial nerve VII.
4. A patient asks a nurse the following question: Exposure to TB can be best identified with which of the following procedures?
- A. Chest x-ray
- B. Mantoux test
- C. Breath sounds examination
- D. Sputum culture for Mycobacterium tuberculosis
Correct answer: B
Rationale: The Mantoux test, also known as the tuberculin skin test, is the most appropriate and accurate test to identify exposure to TB. This test involves injecting a small amount of PPD tuberculin under the top layer of the skin, and a positive reaction indicates exposure to the TB bacteria. Choice A, a chest x-ray, is useful for detecting active TB disease but not exposure. Choice C, a breath sounds examination, is not a specific test for TB exposure. Choice D, a sputum culture for Mycobacterium tuberculosis, is used to diagnose active TB infection rather than exposure.
5. Herbal therapy has several indications for use. Primarily, herbal therapy is:
- A. used to treat many common complaints and diseases.
- B. used to promote certain types of low-carb diets.
- C. used as an adjunct to medications.
- D. used to create a diet without salt and carbohydrates.
Correct answer: A
Rationale: The correct answer is A: 'used to treat many common complaints and diseases.' Herbal therapy is commonly used to address a variety of health issues and ailments by utilizing natural remedies derived from plants. Choices B, C, and D are incorrect because herbal therapy's primary purpose is not to promote specific diets, act as an adjunct to medications, or create specific dietary restrictions, but rather to provide alternative treatment options for various health conditions.
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