Nursing Elites

1. High uric acid levels can develop in clients who are receiving chemotherapy. This can be caused by:

• A. the inability of the kidneys to excrete the drug metabolites.
• B. rapid cell catabolism.
• C. toxic effects of the prophylactic antibiotics that are given concurrently.
• D. the altered blood pH from the acidic nature of the drugs.

Correct answer: B

Rationale: The correct answer is 'rapid cell catabolism.' During chemotherapy, rapid cell destruction occurs, leading to an increase in uric acid levels as a byproduct of cell breakdown. High uric acid levels are primarily a result of the rapid breakdown of cells during chemotherapy, not due to the kidneys' inability to excrete drug metabolites (Choice A). The prophylactic antibiotics given concurrently do not directly cause high uric acid levels (Choice C). The altered blood pH from the acidic nature of the drugs (Choice D) is not a direct cause of elevated uric acid levels; the main mechanism is the rapid cell catabolism that occurs during chemotherapy.

2. One drug can alter the absorption of another drug. One drug increases intestinal motility. Which effect does this have on the second drug?

• A. None; absorption of the second drug is not affected.
• B. The increased gut motility decreases the absorption of the second drug.
• C. The absorption of the second drug cannot be predicted.
• D. Less of the second drug is absorbed.

Correct answer: D

Rationale: When one drug increases intestinal motility, it accelerates the movement of the second drug through the system. Since most oral medications are absorbed in the intestine, the faster transit time decreases the absorption of the second drug. Therefore, less of the second drug is absorbed. Choice A is incorrect because the increased gut motility does affect the absorption of the second drug. Choice C is incorrect as the effect of increased intestinal motility on drug absorption can be predicted based on pharmacokinetic principles. Choice B is incorrect as increased gut motility would not increase but decrease the absorption of the second drug.

3. Which of the following individuals is at the highest risk for suicide?

• A. 76-year-old widow with chronic renal failure
• B. 19-year-old with new SSRI therapy
• C. 28-year-old post-partum crying weekly
• D. 50-year-old client with obsessive-compulsive disorder (OCD) and depression

Correct answer: A

Rationale: The correct answer is the 76-year-old widow with chronic renal failure. Elderly individuals with chronic diseases, especially men, are at very high risk for suicide. The other choices, although they may be vulnerable populations, do not carry as high a risk for suicide. The 19-year-old with new SSRI therapy may actually have a lower risk as they are receiving treatment. The 28-year-old post-partum individual is experiencing a common emotional response after childbirth, which is not necessarily indicative of a high suicide risk. The 50-year-old with OCD and depression is at risk but not as high as elderly individuals with chronic illness.

4. A client is having psychological counseling for problems communicating with his mother. Which model of stress is the most useful in reference to this stressor?

• A. Adaptation Model
• B. Stimulus-Based Model
• C. Transaction-Based Model
• D. Selye's Model of Stress

Correct answer: C

Rationale: The Transaction-Based Model, proposed by R.S. Lazarus, is the most relevant model of stress in the context of a client facing communication issues with his mother. This model takes into consideration individual differences and cognitive processes that occur between a stressor and the individual's response. It emphasizes the importance of how the individual perceives and interprets the stressor, incorporating mental and psychological components. In this scenario, the client's difficulties in communicating with his mother involve complex cognitive processes and individual perceptions, making the Transaction-Based Model the most suitable choice. The other options are not as relevant in this context: the Adaptation Model focuses on adjustment to stress over time, the Stimulus-Based Model emphasizes external factors as stressors, and Selye's Model of Stress mainly centers on the physiological response to stress.

5. A 27-year-old woman has delivered twins in the OB unit. The patient develops a condition of 5-centimeter diastasis recti abdominis. Which of the following statements is the most accurate when instructing the patient?

• A. Avoid sit-ups to prevent worsening the condition.
• B. Surgery is not always necessary for this condition.
• C. Guarding the abdominal region is important at this time.
• D. Antibiotics are not needed for diastasis recti abdominis.

Correct answer: C

Rationale: After experiencing diastasis recti abdominis, it is crucial for the patient to protect and guard the abdominal region to facilitate healing. Choice A is correct since avoiding sit-ups is important to prevent worsening the condition by increasing intra-abdominal pressure. Choice B is accurate as not all cases of diastasis recti abdominis require surgery; conservative management is often effective. Choice D is also correct as antibiotics are not indicated for diastasis recti abdominis since it is a separation of the abdominal muscles and not an infectious condition.

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