Nursing Elites

1. Which of the following factors does NOT affect the rate of dissolution of a solute in a solvent?

• A. Temperature
• B. Pressure
• C. Surface area
• D. Particle size

Correct answer: B

Rationale: Pressure does not affect the rate of dissolution of a solute in a solvent. The factors that do affect the rate of dissolution include temperature, surface area, and particle size. Temperature generally increases the rate of dissolution as it provides more energy for the solute particles to break apart and mix with the solvent. Increasing the surface area of the solute by grinding it into smaller particles or increasing its contact area with the solvent can also speed up dissolution. Similarly, reducing the particle size of the solute can increase the rate of dissolution by providing more surface area for interaction with the solvent.

2. What are the finger-like projections that increase the surface area for absorption in the small intestine called?

• A. Crypts of Lieberkühn
• B. Goblet cells
• C. Villi
• D. Paneth cells

Correct answer: C

Rationale: Rationale: A) Crypts of Lieberkühn are small pits in the lining of the small intestine that contain cells involved in the production of intestinal juices, but they do not increase the surface area for absorption. B) Goblet cells are specialized cells that secrete mucus to protect the lining of the digestive tract, but they do not increase the surface area for absorption. C) Villi are finger-like projections in the small intestine that increase the surface area available for nutrient absorption. Each villus contains blood vessels and lacteals (lymphatic vessels) that help absorb nutrients from digested food. D) Paneth cells are specialized cells found in the small intestine that secrete antimicrobial substances, but they do not increase the surface area for absorption.

3. What is the functional group present in ethers?

• A. Hydroxyl
• B. Carbonyl
• C. Ether
• D. Amine

Correct answer: C

Rationale: Ethers have the functional group -O-, representing an oxygen atom bonded to two alkyl or aryl groups. The other choices are associated with different functional groups.

4. In what way does spindle fiber dynamics and microtubule attachment regulate cell cycle checkpoints?

• A. Misaligned chromosomes fail to attach to microtubules, triggering a delay in anaphase onset.
• B. The presence of unattached kinetochores on the centromeres sends a signal to pause cell cycle progression.
• C. Microtubule instability and rapid depolymerization lead to the activation of checkpoint proteins.
• D. All of the above.

Correct answer: D

Rationale: Rationale: A) Misaligned chromosomes fail to attach to microtubules, triggering a delay in anaphase onset: During cell division, proper attachment of chromosomes to spindle fibers is crucial for accurate segregation of genetic material. If chromosomes are not correctly attached to microtubules, it can lead to misalignment, which triggers a delay in anaphase onset. This delay allows the cell to correct any errors before proceeding with cell division. B) The presence of unattached kinetochores on the centromeres sends a signal to pause cell cycle progression: Kinetochores are protein structures located at the centromere of chromosomes and are responsible for attaching chromosomes to spindle fibers. When kinetochores are unattached or improperly attached to microtubules, it sends a signal to the cell to pause cell cycle progression. This pause allows the cell to ensure that all chromosomes are properly aligned before proceeding with cell division.

5. What are isotopes?

• A. Atoms of the same element with different numbers of protons.
• B. Atoms of the same element with different numbers of neutrons.
• C. Atoms of different elements with the same number of protons.
• D. Atoms of different elements with the same number of electrons.

Correct answer: B

Rationale: Isotopes are atoms of the same element that have the same number of protons but different numbers of neutrons. This means that isotopes have the same atomic number (Z) but different mass numbers (A). For example, carbon-12 (¹²C), carbon-13 (¹³C), and carbon-14 (¹⁴C) are all isotopes of carbon. They all have six protons in their nuclei, but they have different numbers of neutrons: carbon-12 has six neutrons, carbon-13 has seven neutrons, and carbon-14 has eight neutrons.

6. What is the term for a genetic disorder caused by a mutation in a mitochondrial gene?

• A. Autosomal dominant disorder
• B. Autosomal recessive disorder
• C. Sex-linked disorder
• D. Mitochondrial disorder

Correct answer: D

Rationale: Rationale: A) Autosomal dominant disorder: This type of genetic disorder is caused by a mutation in one copy of an autosomal gene. It is not related to mitochondrial gene mutations. B) Autosomal recessive disorder: This type of genetic disorder is caused by mutations in both copies of an autosomal gene. It is not related to mitochondrial gene mutations. C) Sex-linked disorder: This type of genetic disorder is caused by mutations in genes located on the sex chromosomes (X or Y). It is not related to mitochondrial gene mutations. D) Mitochondrial disorder: Mitochondrial disorders are genetic disorders caused by mutations in genes located in the mitochondria, the energy-producing structures within cells. These disorders are inherited maternally and can affect various organs and systems in the body due to the role of mitochondria in energy production.

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