Nursing Elites

1. What are chromosomes made of?

• A. DNA and RNA
• B. DNA and proteins
• C. Proteins and carbohydrates
• D. DNA only

Correct answer: B

Rationale: Rationale: Chromosomes are structures found in the nucleus of cells that contain genetic material. They are made up of DNA (deoxyribonucleic acid), which carries the genetic information, and proteins that help in the organization and packaging of the DNA. While RNA is involved in various cellular processes, it is not a major component of chromosomes. Carbohydrates are not a significant component of chromosomes. Therefore, the most accurate answer is B) DNA and proteins.

2. What is the purpose of the spindle apparatus in cell division?

• A. To separate sister chromatids
• B. To move chromosomes to opposite poles of the cell
• C. To form a new nuclear envelope around each daughter cell
• D. To synthesize new DNA

Correct answer: B

Rationale: Rationale: The spindle apparatus is a structure composed of microtubules that plays a crucial role in cell division (mitosis and meiosis). Its main purpose is to ensure the proper separation and distribution of chromosomes to opposite poles of the cell during cell division. This process is essential for the formation of two genetically identical daughter cells in mitosis or four haploid daughter cells in meiosis. Option A is incorrect because the separation of sister chromatids specifically refers to the role of the kinetochore fibers within the spindle apparatus. Option C is incorrect because the formation of a new nuclear envelope occurs after the chromosomes have been properly segregated. Option D is incorrect because DNA synthesis does not occur within the spindle apparatus; it takes place during the S phase of the cell cycle.

3. Describe the ethical considerations surrounding the potential use of CRISPR-Cas9 technology in humans.

• A. Concerns about unintended consequences on the genome and potential off-target effects.
• B. Debates on modifying the human germline and potential eugenic implications.
• C. Accessibility and affordability of the technology, ensuring equitable access to benefits.
• D. Risks associated with CRISPR-Cas9 editing germline cells and potential long-term impacts.

Correct answer: B

Rationale: CRISPR-Cas9's ability to precisely edit germline cells raises ethical dilemmas about modifying the human gene pool. This includes concerns about eugenics, unintended consequences, and the long-term impact on future generations.

4. Stephanie is a new Staff Educator of a private tertiary hospital. She conducts orientation

• A. Organizational structure
• B. Policy
• C. Job description
• D. Manual of procedures

Correct answer: D

Rationale: The correct answer is D, 'Manual of procedures.' During orientation, Stephanie as a Staff Educator would likely refer to the manual of procedures to provide new employees with detailed instructions on how to perform their job duties. This manual outlines the specific procedures, protocols, and guidelines that employees are expected to follow within the organization. It serves as a valuable resource for new hires to understand the standard operating procedures and expectations within the hospital setting, making it a crucial document to reference during orientation.

5. Which type of joint allows for the widest range of motion, like the shoulder joint?

• A. Hinge joint
• B. Ball-and-socket joint
• C. Gliding joint
• D. Fixed joint

Correct answer: B

Rationale: The correct answer is B: Ball-and-socket joint. A ball-and-socket joint, like the shoulder joint, allows for the widest range of motion in all directions, including flexion, extension, abduction, adduction, and rotation. This type of joint consists of a rounded, ball-like end of one bone fitting into a cup-like socket of another bone, providing great mobility and flexibility. Hinge joints, like the elbow, only allow movement in one plane (like a door hinge), gliding joints permit limited sliding movements between bones, and fixed joints, such as those in the skull, have no movement at all.

6. Differentiate between genotype and phenotype in the context of gene expression.

• A. Genotype refers to the physical manifestation of a trait, while phenotype represents its underlying genetic makeup.
• B. Genotype encompasses the spectrum of possible traits encoded by an organism's genes, while phenotype signifies the specific trait observed.
• C. Genotype denotes the presence of dominant alleles, while phenotype reflects the influence of recessive alleles.
• D. There is no distinction; both terms are interchangeable.

Correct answer: B

Rationale: Rationale: - Genotype refers to the genetic makeup of an organism, including all the genes and alleles it possesses. - Phenotype, on the other hand, refers to the observable physical characteristics or traits of an organism, which result from the interaction between its genotype and the environment. - While genotype represents the genetic potential or range of traits that an organism can express, phenotype reflects the actual expression of specific traits. - Therefore, option B correctly captures the distinction between genotype and phenotype in the context of gene expression.

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