Nursing Elites

1. In what way does spindle fiber dynamics and microtubule attachment regulate cell cycle checkpoints?

• A. Misaligned chromosomes fail to attach to microtubules, triggering a delay in anaphase onset.
• B. The presence of unattached kinetochores on the centromeres sends a signal to pause cell cycle progression.
• C. Microtubule instability and rapid depolymerization lead to the activation of checkpoint proteins.
• D. All of the above.

Correct answer: D

Rationale: Rationale: A) Misaligned chromosomes fail to attach to microtubules, triggering a delay in anaphase onset: During cell division, proper attachment of chromosomes to spindle fibers is crucial for accurate segregation of genetic material. If chromosomes are not correctly attached to microtubules, it can lead to misalignment, which triggers a delay in anaphase onset. This delay allows the cell to correct any errors before proceeding with cell division. B) The presence of unattached kinetochores on the centromeres sends a signal to pause cell cycle progression: Kinetochores are protein structures located at the centromere of chromosomes and are responsible for attaching chromosomes to spindle fibers. When kinetochores are unattached or improperly attached to microtubules, it sends a signal to the cell to pause cell cycle progression. This pause allows the cell to ensure that all chromosomes are properly aligned before proceeding with cell division.

2. An IV bag contains 500ml of saline solution and needs to be infused over 4 hours. What is the flow rate in drops per minute, assuming 20 drops per milliliter?

• A. 12.5 drops/min
• B. 25 drops/min
• C. 50 drops/min
• D. 100 drops/min

Correct answer: C

Rationale: Calculate the total volume in drops (500ml * 20 drops/ml = 10,000 drops). Divide this by the infusion time in minutes (4 hours * 60 minutes/hour = 240 minutes) to get the flow rate.

3. Which of the following organs is responsible for churning and mechanically breaking down food?

• A. Small intestine
• B. Large intestine
• C. Stomach
• D. Esophagus

Correct answer: C

Rationale: Rationale: The stomach is responsible for churning and mechanically breaking down food. It contains muscles that contract and relax to mix food with digestive juices, breaking it down into smaller particles. This mechanical digestion process helps prepare the food for further digestion and absorption in the small intestine. The small intestine is primarily responsible for the absorption of nutrients, the large intestine absorbs water and salts, the esophagus is a muscular tube that transports food from the mouth to the stomach.

4. Half-life refers to the characteristic time it takes for:

• A. Radioactive intensity to completely disappear
• B. The number of neutrons in a nucleus to double
• C. The number of protons in a nucleus to change
• D. An isotope to decay by half of its initial quantity

Correct answer: D

Rationale: The correct answer is D: An isotope to decay by half of its initial quantity. The half-life of a substance is the time it takes for half of the initial quantity of radioactive atoms to decay. This is a characteristic property of each radioactive isotope and is used to determine the rate of decay of a substance. Option A is incorrect because radioactive intensity does not completely disappear in half-life, it only decreases by half. Options B and C are unrelated to the concept of half-life and do not accurately describe its definition.

5. You need to paint a rectangular swimming pool with dimensions 8m by 5m and a depth of 2m. Considering only the interior walls and floor (not the top), how much paint do you need (assume one can of paint covers 10 sq m)?

• A. 56 sq m
• B. 72 sq m
• C. 88 sq m
• D. 104 sq m

Correct answer: C

Rationale: Calculate the areas of each wall and the floor, sum them up, and subtract the area of the water surface (top). Divide the final area by the coverage area per can to determine the number of cans needed.

6. The human body's largest organ, responsible for detoxification and a multitude of other functions, is the:

• A. Heart
• B. Liver
• C. Lungs
• D. Skin

Correct answer: B

Rationale: The correct answer is B: Liver. The liver is the largest internal organ in the human body and is responsible for detoxification, processing nutrients, producing bile, and regulating blood sugar levels, among other functions. While the heart is vital for pumping blood, the lungs are crucial for respiration, and the skin is the body's largest external organ, the liver plays a central role in detoxification and various metabolic processes, making it the correct answer to this question.

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