Nursing Elites

1. In what way does spindle fiber dynamics and microtubule attachment regulate cell cycle checkpoints?

• A. Misaligned chromosomes fail to attach to microtubules, triggering a delay in anaphase onset.
• B. The presence of unattached kinetochores on the centromeres sends a signal to pause cell cycle progression.
• C. Microtubule instability and rapid depolymerization lead to the activation of checkpoint proteins.
• D. All of the above.

Correct answer: D

Rationale: Rationale: A) Misaligned chromosomes fail to attach to microtubules, triggering a delay in anaphase onset: During cell division, proper attachment of chromosomes to spindle fibers is crucial for accurate segregation of genetic material. If chromosomes are not correctly attached to microtubules, it can lead to misalignment, which triggers a delay in anaphase onset. This delay allows the cell to correct any errors before proceeding with cell division. B) The presence of unattached kinetochores on the centromeres sends a signal to pause cell cycle progression: Kinetochores are protein structures located at the centromere of chromosomes and are responsible for attaching chromosomes to spindle fibers. When kinetochores are unattached or improperly attached to microtubules, it sends a signal to the cell to pause cell cycle progression. This pause allows the cell to ensure that all chromosomes are properly aligned before proceeding with cell division.

2. What term describes the phenomenon of two waves canceling each other out when they meet?

• A. Refraction
• B. Diffraction
• C. Destructive interference
• D. Constructive interference

Correct answer: C

Rationale: Destructive interference occurs when two waves meet and their amplitudes are such that they cancel each other out, resulting in a wave with a smaller amplitude or no wave at all. This is in contrast to constructive interference, where two waves combine to produce a wave with a larger amplitude. Refraction and diffraction are phenomena related to the bending of waves as they pass through different mediums or obstacles, respectively.

3. A diabetic patient's blood sugar is 180mg/dL. Their usual insulin dose is 1 unit per 40mg/dL above 100mg/dL. How much insulin should be administered?

• A. 2 units
• B. 3 units
• C. 4 units
• D. 5 units

Correct answer: B

Rationale: Rationale: 1. Calculate the excess blood sugar above 100mg/dL: 180mg/dL - 100mg/dL = 80mg/dL. 2. Determine the insulin dose based on the patient's usual insulin dose: 80mg/dL / 40mg/dL = 2 units. 3. Add the calculated insulin dose to the patient's usual insulin dose: 1 unit (usual dose) + 2 units (calculated dose) = 3 units. Therefore, the correct answer is 3 units of insulin should be administered to the diabetic patient with a blood sugar level of 180mg/dL.

4. Identify the determiner in the following sentence: A few birds chirped happily in the branches of the tall tree.

• A. happily
• B. ranches
• C. few
• D. tree

Correct answer: C

Rationale: Determiners specify the quantity or identity of a noun. "Few" indicates the number of birds.

5. In the reaction 4Al + 3O2 → 2Al2O3, what is the mole ratio of aluminum to oxygen?

• A. 4:3
• B. 2:3
• C. 3:2
• D. 3:4

Correct answer: a

Rationale: The coefficients in the balanced equation represent the mole ratio, which is 4 moles of Al to 3 moles of O2.

6. Which term describes the resistance of a substance to being hammered into different shapes?

• A. Viscosity
• B. Ductility
• C. Malleability
• D. Conductivity

Correct answer: c

Rationale: Malleability refers to the resistance of a substance to being hammered or pressed into different shapes without breaking.

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